Fiber Optic Sensor System Dissolution
A dissolution system provides remote flow cells integrated into a manifold device.
Fiber optic sensor system dissolution. A commercially viable strategy for cell therapy manufacturing. In situ fiber optic uv for dissolution testing. A fiber optic sensor is a sensor that uses optical fiber either as the sensing element intrinsic sensors or as a means of relaying signals from a remote sensor to the electronics that process the signals extrinsic sensors. Fibers have many uses in remote sensing.
Liquid samples are respectively drawn from dissolution vessels optically related measurements are taken and the samples are. Depending on the application fiber may be used because of its small size or because no electrical power is needed at the. Bility of using fiber optic technology for special dissolution applications. Gemperline et al 8 applied a ccd fiber optic system for determining two component dissolu tion profiles of a pharmaceutical product which.
It is especially applicable for on line and in situ monitoring of therapeutic drugs in biological samples its great potential can be fully brought out by use of computers. Fiber optic sensors are useful in that the sample need not be in a spectrometer. Hanson research is proud to collaborate with pion to offer fiber optic dissolution monitoring for dissolution labs around the world. For example chen and his group 6 7 employed a fiber optic based chemical sensor for continuous monitoring of in situ dissolu tion.
The measurement of dissolution of solid preparations is required by regulatory agencies pharmaceutical factories and. The distek opt diss 410 in situ fiber optic uv system measures directly in the vessel eliminating all the issues associated with conventional sampling.